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Only a small subset of these genes was associated with ASD, while the large number of affected genes suggests a broad modulatory impact on the CNS, particularly on genes involved in synaptic function and neurotransmission [85]
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Zinc has been shown to block hypoxia-stimulated HIF-1α nuclear translocation and subsequently disrupting HIF-1 heterodimerization as well as to induce HIF-1α proteasomal degradation 32
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