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Downstream of MET activation the signaling is well characterized and is not in dispute as general biology: MET phosphorylation recruits GAB1 and GRB2 and drives PI3K/AKT and MAPK/ERK cascades
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Post-infusion CAR T cells in bone marrow (BM) of LTR have high immunometabolic plasticity and mTOR-pS6 expression supported by the BM microenvironment
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