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Work from David Savage’s group showed that PLIN1 mutations from patients with lipodystrophies, which lack the C-terminus, fail to stabilize ABHD5 on LDs, resulting in greater basal lipolysis (137) and likely explains why these patients are unable to sequester FAs into TAGs
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BPC 157, short for Body Protective Compound 157, is a 15-amino acid peptide originally extracted from human gastric juice
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