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The second model is based on the antigen gene expressed in vivo, including viral vector vaccines (using replication-defective engineered viruses carrying the mRNA of S protein or RBD), DNA vaccines (DNA sequences of S protein or RBD), and mRNA vaccines (RNA sequences of S protein or RBD)
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There was an overall weight gain in these patients and a decrease in the frequency of clinical signs such as vomiting and diarrhea
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