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As mentioned above, the current set of studies have their limitations and should be used to design and implement well-controlled blinded randomized clinical trials in the future
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In vitro, 5-amino-1MQ is characterized as a selective inhibitor of NNMT (nicotinamide N-methyltransferase), the enzyme that methylates nicotinamide, and is used as the reference inhibitor in NNMT enzymatic assays
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