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The inherent risks associated with these invasive methods, particularly in patients with compromised health, underscore the importance of alternative diagnostic approaches (100)
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[5] The methylation cycle hypothesis states that many if not all of the symptoms of CFS are caused by errors in the genes that regulate or have a strong impact on one-carbon metabolism, such as MTHFR, CBS, DHPR, MTRR, or MAO-A
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