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This underscores the therapeutic potential of enhancing the functionality of the antioxidant axis to treat UC targetting ferroptosis ( Nrf2 /GPX4 signaling, increasing GPX4 activity, inhibiting ferroptosis, and improving intestinal barrier integrity ( Nrf2 /GPX4 signaling, increase GPX4 activity, inhibit ferroptosis, and treat UC (Wu et al., 2023)
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