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Although it supplies sulfhydryl group (-SH) groups and provides cysteine for GSH synthesis, NAC’s direct reactivity with major physiological oxidants such as H 2 O 2 and O 2 • − is too slow to exert meaningful scavenging activity ( 2 O 2 ( Erdosteine also demonstrates significant antioxidant activity ( 2 • − , H 2 O 2 , NO, and lysosomal enzymes from activated macrophages
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Optimal medical therapy for stable ischemic heart disease: focus on anti-anginal therapy
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