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To effectively assess the degree of radiation induced skin injury (RISI), the RTOG, CTCAE and RISRAS scales are used ( RTOG (radiation therapy oncology group) One of the most widely used grading system for Radiation-Induced adverse reactions including skin toxicities is RTOG scale ( CTCAE (common terminology criteria for adverse events) In clinical trials, the clinicians typically use the National Cancer Institute (NCI)’s Common Terminology Criteria for Adverse Events to report the Adverse Events (AEs)

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Large amounts of diethyl maleate (DEM) and monocarboxylate transporter 4-inhibiting siRNA (siMCT4) were released after treatment with 10 × 10 −3 M H 2 O 2