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A Study of Vitamin B12 Requirements in a Patient With Pernicious Anemia and Thyrotoxicosis: Evidence of an Increased Need for Vitamin B12 in the Presence of Hyperthyroidism - ScienceDirect

* * * * * (b) * * * (3) * * * (ii) Direct supervision in the office setting means that the physician (or other supervising practitioner) must be present in the office suite and immediately available to furnish assistance and direction throughout the performance of the service

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For instance, large amounts of vitamin B₆ can increase the metabolism of phenytoin or phenobarbital, potentially lowering their blood levels and reducing seizure control

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