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Methods Two sets of in silico experiments were performed using molecular docking simulations to determine the influence of hGH fragment 176–191 peptide on the anticancer efficacy of doxorubicin 1) the binding affinities of hGH fragment 176–191 peptide to the breast cancer receptors, 2) the effects of hGH fragment 176–191 peptide binding on doxorubicin binding to these same receptors

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WangLTangCCaoHLiKPangXZhongLet alActivation of IL-8 via PI3K/akt-dependent pathway is involved in leptin-mediated epithelial-mesenchymal transition in human breast cancer cells