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340 Binding immune complexes (ICs) to FcγRIIa activates neutrophils, triggering cellular responses such as degranulation, cytoskeletal reorganization, production of ROS and inflammatory mediators, and the generation of NETs
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These studies signal the likely activation of the NRF2 pathway in these cell types, but optimization of dose, formulation, timeframe and tissue processing have not been undertaken rigorously to date
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