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The neuropathic pain has been described as a burning and aching irritation which increases the sensitivity of the skin.[5] Clinical trials have indicated methylcobalamin’s potential in reducing the occurrence and frequency of neuropathic pain associated with diabetes.[6] The studies observed the reduction in overall pain scale score in neuropathic pain after consumption of methylcobalamin

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It is used in the treatment and prevention of vitamin B12 deficiency in patients with conditions such as: Addisonian (pernicious) anemia Malabsorption Atrophic gastritis Prolonged treatment with metformin Small bowel bacterial overgrowth (SIBO) Total or partial gastrectomy Infection with the fish parasite Diphyllobothrium latum Helicobacter pylori infection Pancreatic dysfunction Pancreatic or bowel malignancy Dietary deficiency (e.g