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Glycine and Anxiety Reduction Glycine functions as an inhibitory neurotransmitter, particularly within the spinal cord and brainstem.⁶ It also modulates the NMDA Receptor, an important receptor involved in: Stress response Mood regulation Memory formation Neuroplasticity Research suggests glycine may help reduce: Mild anxiety states Hyperarousal Stress-induced insomnia Racing thoughts at bedtime⁶˒⁷ Unlike benzodiazepines, glycine generally does not produce dependency or significant morning sedation