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As mentioned, β 1 -ARs display agonist-induced downregulation chiefly due to decreases in mRNA levels (Liu et al., 2019
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the myostatin-selective inhibitor is an antibody or antigen-binding fragment thereof comprising the heavy and light chain variable domains of any one of Ab101-Ab141 , e.g., the pair of SEQ ID NOs identified for a specific antibody in Table 3
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