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“Genome-wide DNA modification profiling” includes studies in which drug-induced DNA modifications were assessed using a genome-wide or whole-genome approach (i.e., microarray or next-generation sequencing)
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The data in Figure 6 represent the results of vitamin B-12–deficient patients who were mistakenly prescribed daily doses of folic acid (0.4–1.0 mg) for 12 to 67 d before measurement of tHcy and MMA, followed by subsequent correction by vitamin B-12 administration
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