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To test whether GlyNAC supplementation in OA could improve GSH deficiency, OxS, mitochondrial dysfunction, IR, physical function, and aging hallmarks, we conducted a placebo-controlled randomized clinical trial

Muscletech

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Summary Knee OA has recently been described as an evolutionary ‘mismatch disease’ based on the apparent inability of genes inherited from prior populations to adequately adapt to the rapid changes in factors associated with OA pathogenesis, such as obesity, metabolic syndrome, dietary changes, and physical inactivity (7)