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Term Half-life What it means Time related to drug clearance What the evidence says About 2 hours after IV infusion in the 1999 human PK/PD study Term GH response window What it means Short hormone response after exposure What the evidence says GH peaked near 0.67 hours in the 1999 IV study Term Cycle length What it means Total weeks in a repeated schedule What the evidence says No validated 8-, 12-, or 16-week SC duration Term Off cycle What it means Planned period without exposure What the evidence says No validated 4-week washout rule in human Ipamorelin trials What Do We Know About Long-Term Ipamorelin Use