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102,356 Furthermore, evodiamine, a natural compound, has been identified to impair H3K18la to inhibit angiogenesis and ferroptosis in PCa
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This combination paradigm is based on the principle of a one-two punch the first agent acts to prime the cancer cell by inducing metabolic stress and creating a sharp state of vulnerability, while the second agent delivers the lethal ferroptotic blow by disabling the already-strained antioxidant defenses
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