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Keywords: myalgic encephalomyelitis/chronic fatigue syndrome, pathology, treatment, pathophysiology, diagnostic criteria Introduction Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) or Systemic Exertion Intolerance Disease (SEID) (1–3) (hereafter referred to as ME/CFS) is a debilitating chronic multisystem illness

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