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141,142 Secondly, Akkermansia muciniphila can regulate the hepatic immune microenvironment through the TLR2-γδT17 cell axis by secreting cytokines such as IL-17A and IL-22 as well as regulating the conversion of macrophages into anti-inflammatory macrophages, which in turn reduces hepatic inflammation
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This, in turn, activates Bcl-2, leading to ectopic endometrial cell resistance to apoptosis and proliferation
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