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However, the achieved demonstration of the beneficial effects, and thereby stomach cytoprotection → organoprotection more reliable realization, involves the whole gastrointestinal tract, both prophylactic and therapeutic effect, including the pre-existing lesions in the most complex disturbances, such as the internal and external fistulas, or anastomosis complicated with severe colitis

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Assessment of oxPTM-CII in a mouse model of OA revealed early occurrences of oxidant production and chondrocyte hypertrophy, potentially initiating the pathological processes of OA (119)