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Consistent with the importance of GSH in hepatic fibrogenesis, we found that a lower hepatic GSH level greatly potentiated BDL-induced fibrosis and if induction in GCLC expression was blocked (by using RNAi), the therapeutic efficacy of UDCA and SAMe was nearly lost [174]
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10.1016/S0925-4773(00)00466-4 [DOI] [PubMed] [Google Scholar] Talbott J
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