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mBCl [Monochlorobimane] *CAS 76421-73-3* | AAT Bioquest
The inclusion criteria were the age range of 18–60 years with clinically definite relapsing–remitting MS (RRMS) diagnosed based on McDonald criteria and an Expanded Disability Status Scale (EDSS) score ≤4.5, a score of 8–15 (mild‐to‐moderate anxiety and depression) from the Hospital Anxiety and Depression Scale (HADS) questionnaire in depression (HADS‐D) and anxiety (HADS‐A) subscales, no history of severe depression, anxiety, suicide attempt, and any chronic diseases, lack of consuming medications including antidepressants, fatigue modulating drugs, or drugs that would interact with NAC or affect its metabolism, no history of drug or alcohol addiction, lack of consuming oral or systemic glucocorticoids and any regular intake of antioxidants or vitamin supplements within 30 days prior to the study, and lack of pregnancy or lactation
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Leptin levels are significantly higher in individuals with obesity compared to those with normal weight, and a substantial correlation exists between leptin levels and BMI (94, 95)
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