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Iron accumulation and lipid peroxidation in β-cells, driven by mitochondrial dysfunction and inflammatory cytokines like IL-1β and IFN-γ produced by T cells and macrophages, lead to β-cell dysfunction and apoptosis (105, 106, 109, 146)
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doi: 10.1186/s12931-019-1164-1 155 CuiJWangYTianXMiaoYMaLZhangCet al
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