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Central obesity as a precursor to the metabolic syndrome in the AusDiab study and Mauritius
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In primary liver cancer models in vivo and TGF-Ξ²1-induced human HCC (HepG2) cells in vitro, AS-IV can promote Nrf2/HO-1/NQO1 signaling transduction and upregulate the antioxidant activity of pNrf2 and its downstream proteins to alleviate the progression of liver fibrosis and primary liver cancer (167,180)
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