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Targeting ACSL4-dependent lipid remodeling or enhancing FSP1-mediated antioxidant defense provides additional strategies to modulate ferroptosis in disease contexts
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Intraperitoneal (IP) or intravenous (IV) injections of various drugs, ranging from MTX, 5-FU, CP, doxorubicin (DOX), DCTX, PCTX, cisplatin to thioTEPA were shown to increase the impairment of memory and decreased numbers of NPCs, immature or mature neurons (Nguyen and Ehrlich, 2020)
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