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▶ ▶ Adult (body-weight up to 38 kg): 150 micrograms/kg once daily on alternate days for maximum duration of treatment 4 months, two consecutive doses may be given 24 hours apart if no response to treatment on the preceding day Adult (body-weight 38–61 kg): 8 mg once daily on alternate days for maximum duration of treatment 4 months, two consecutive doses may be given 24 hours apart if no response to treatment on the preceding day (Books-Courses-Medical Applications) Constipation 67 Adult (body-weight 62–114 kg): 12 mg once daily on alternate days for maximum duration of treatment 4 months, two consecutive doses may be given 24 hours apart if no response to treatment on the preceding day ▶ Adult (body-weight 115 kg and above): 150 micrograms/kg once daily on alternate days for maximum duration of treatment 4 months, two consecutive doses may be given 24 hours apart if no response to treatment on the preceding day PHARMACOKINETICS ▶ May act within 30–60 minutes