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Excessive iron promotes hydroxyl radical (•OH) generation via the Fenton reaction, thereby exacerbating lipid peroxidation and oxidative injury, which in turn facilitates Aβ aggregation, tau hyperphosphorylation, and neuronal degeneration (Pei et al., 2025
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McCaul JA, Cascarini L, Godden D, Coombes D, Brennan PA, Kerawala CJ
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