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The intrinsic pathway is tightly regulated by the BCL2 apoptosis regulator (BCL2) protein family, which includes both pro-apoptotic members (e.g., Bcl2-Associated X Protein (BAX), Bcl2 Antagonist/Killer (BAK), Bcl2 Interacting Mediator of cell Death (BIM)) and anti-apoptotic members (e.g., BCL2, B Cell lymphoma-extra large (BCL-XL), Myeloid Cell Leukemia-1 (MCL-1))
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It will therefore be of future interest to understand how these hybrid complexes function and the nature of the lipoate intermediates that form
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