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If you’re considering adding coffee enemas into a broader detox or gut-healing plan, working with a qualified functional medicine provider ensures you’re doing it safely and effectively.These individuals should not perform coffee enemas: Those with inflammatory bowel disease (Crohn’s, UC) Severe hemorrhoids Kidney disease Heart rhythm disorders Pregnant individuals Those sensitive to caffeine Consult a licensed medical provider before starting any detox or gastrointestinal protocol

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In vitro, experimental evidence shows that these Aβ deposits induce cerebrovascular dysfunction in the rat brain [220] and that the Aβ peptide produces endothelial dysfunction in cerebral microvessels via ROS