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For example, a reduction in collagen fibers, matrix degradation, and failure of incision healing are observed in a skin incision model in Spp1-knockout mice, suggesting a role for Spp1 in wound repair processes (Heinemeier et al., 2012
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It is well known that it is necessary to examine different parameters to evaluate the antioxidant capacity of a compound such as the interaction with other antioxidant molecules, the specificity in the elimination of free radicals, the metal-chelating ability, the outcomes on gene expression, the capability to repair oxidative injury, and the bioavailability [10]
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