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Once recruited to the site of injury, rod microglia have the ability to degrade the extracellular matrix, to promote the retraction of dystrophic axons and to disrupt synapses, in a phenomenon known as “synaptic stripping,” decreasing synaptic activity and metabolic requirement of the damaged neurons (Perry and O’Connor, 2010

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Extent of Absorption After oral administration, a drug may be incompletely absorbed, eg, only 70% of a dose of digoxin reaches the systemic circulation