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Mechanistically, this may involve direct binding to the SLC7A11 genomic locus by p53 [84], or modulation of histone H2B monoubiquitination in the vicinity of the SLC7A11 locus by USP7, which can be recruited to the nucleus by p53 [85]
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Growth Hormone Secretion: Growth hormone (GH) is secreted from the somatotroph cells of the pituitary gland
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