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Elevated Bcl-2/Bax ratio and reduced cleaved caspase-3/PARP levels indicate anti-apoptotic mechanism
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5-Amino-1MQ has been investigated in preclinical models as a selective inhibitor of NNMT, an enzyme that catalyses the methylation of nicotinamide and has been referenced in the literature in connection with cellular energy metabolism, NAD+-associated signalling pathways, and energy homeostasis
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