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Frontiers | Mechanisms and therapeutic strategies of macrophages and neutrophils inducing ulcerative colitis progression

Treatment with silymarin significantly decreased AST (SMD: − 0.916, 95% CI: − 1.437, − 0.394, p -value: 0.001) (Figure S14) and ALT (SMD: − 0.847, 95% CI: − 1.261, − 0.432, p -value: 0.000) (Figure S15) levels in patients with non-alcoholic fatty liver diseases (NAFLD), while it had no substantial effects on liver enzymes in patients with alcoholic liver cirrhosis (Figure S14 and S15)

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Designed to target fat stores specifically