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Among the limitations of this study, the most notable is the inability to perform a meta-analysis due to the great variability of the studies found
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An inflammatory gene PCR array further demonstrated the anti-inflammatory effects of rBDNF in LPS-challenged macrophages, showing that rBDNF suppresses LPS-induced expression of over 40 key inflammatory genes, including chemokines, interleukins, and interferons (Fig
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