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The autophagy adaptor NDP52 and the FIP200 coiled-coil allosterically activate ULK1 complex membrane recruitment | bioRxiv
Ascorbate, dithiothreitol and TCEP reduce copper(II) to copper(I), and the donor set that stabilizes the divalent ion does not stabilize the monovalent one, so the complex is destroyed and the released copper becomes redox-active
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Reference: Kleinman HK & Sosne G (2012)
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