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Four components comprise this transporting system: the carnitine palmitoyltransferase 1 (CPT1) and 2 (CPT2), the carnitine-acylcarnitine translocase (CACT), and the carnitine acetyltransferase (CrAT) that close the carnitine cycle, allowing the export of the FAO-produced acetyl-CoA as acetyl-carnitine (Fig
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The metabolic and appetite-modulating properties of short-chain fatty acids are mediated through their binding to G protein-coupled receptors (e.g., FFAR3 and FFAR2) distributed across multiple tissues
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