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Therefore, based on TCM and Western medicine, the liver has the bidirectional relationships with the extrahepatic organs, and the established bidirectional system by the liver and one extrahepatic organ can further influence another one or more extrahepatic organs or tissues, thus, form a single line or multidimensional interaction network centered on the liver, which has been depicted as the “pan-liver network.” We propose these complex network mechanisms as the “pan-liver network theory,” in this theory, the liver plays an essential role in modulating health and diseases through multiple signals
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In addition to breaking down fats and carbs for energy, it’s responsible for the production of sex and stress-related hormones including testosterone
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