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Enzymes that could be involved are: γ-glutamylcysteine synthetase, glutathione synthetase, glutathione peroxidase, glutathione disulfide reductase, glutathione-S-transferase, GSH or GSSG transport protein, cysteine or cystine transport proteins, glycine transport proteins, glutamate transport proteins, glucose-6-phosphate dehydrogenase, and many others
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This opens avenues for more research to further decipher how coffee or its active ingredients modulate intracellular mechanisms that are related to impaired cardiovascular systems, including energy metabolism, lipid metabolism, glucose uptake, and others
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