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Echinocandin resistance is primarily driven by mutations in FKS1 , while drug-induced cell wall stress can activate tolerance pathways such as the Ca² + /calcineurin and Hsp90/mTOR signaling cascades (Perlin, 2007
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If the policy is unavailable, ask for it rather than filling the gap with expectations. Make the purchase with a clear understanding of the applicable process rather than a presumed universal refund policy.
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