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Such assays require costly equipment, skilled personnel and strict validation

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Mechanism of Action: • Ultra-long acting basal insulin analogue (Insulin Icodec) • Reversibly binds to albumin, creating a circulating depot • Provides stable glucose-lowering activity for approximately 7 days • Designed to maintain consistent basal insulin coverage with a single weekly injection Administration • Subcutaneous injection only • Once weekly, on the same day each week • Injection sites: abdomen, thigh, or upper arm • Supplied as AWIQLI FlexTouch prefilled pen • Concentration: 700 units/mL (U-700) Switching from Daily Basal Insulin A practical dosing strategy: Week 1: One-time loading dose followed by the first weekly dose Week 2 onward: Weekly maintenance dose based on previous total daily basal insulin requirements Dose titration should always be individualized according to fasting glucose and CGM/SMBG readings