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[oai_citation:1‡PubMed]( 2) Nitric-oxide–mediated, largely endothelium-dependent vasorelaxation Aortic ring experiments showed vasodilation that was blunted by L-NAME and hemoglobin and attenuated without endothelium—consistent with NO-mediated effects
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The findings confirmed that AOD-9604 displayed a very good safety and tolerability profile indistinguishable from placebo
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