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Yang and coauthors measured serum levels of thyroid parameters and urinary concentrations of ten phthalates in early pregnancy in 42 Chinese women with a diagnosis of subclinical hypothyroidism (SCH) and 84 euthyroid women matched for age and BMI enrolled between August 2019 and January 2020 [99]
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This sample size was considered adequate for exploratory estimation of exposure differences and variability to inform the design of future confirmatory studies
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