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ZDHHC12, a palmitoyltransferase interacting with APP, inhibits AΞ² production and pathological deposition by blocking APP transport and enhancing non-amyloidogenic Ξ±-cleavage, suggesting that ZDHHC12 may be involved in the early pathogenesis of AD (223)
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Similarly to NCOA4, GPX4 was significantly decreased in the late stage AD pathology (AD2 and AD3 groups) compared to control in GM
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