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In some organisms, such as mycobacteria [135], the γ-glutamyl-cysteine peptide is also used for the synthesis of ergothioneine (hereafter EGT), an unusual thio-histidine betaine amino acid (also known as 2-mercaptohistidine trimethylbetaine) that has potent antioxidant and cytoprotective activities [136,137,138,139,140]
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By binding to HDM-2, PNC-27 induces cell membrane disruption, leading to the selective death of cancer cells while leaving healthy tissues unharmed
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