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My goal is to design an interactive visualization tool (DIVA) that aligns with the drug safety review workflow to support the analysis of these hypothesized drug-drug interaction (DDI) signals
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For example, OTA induced strong down-regulation of regucalcin, which interferes with intracellular calcium regulation, a finding associated with nephrotoxic and nephrocarcinogenic compounds such as cisplatin [74,75]
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