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In stark contrast, the management of nociplastic pain prioritizes nonpharmacological, biopsychosocial interventions, patient education, graded exercise, and cognitive‐behavioral therapy (CBT), as first‐line care, with pharmacotherapy playing a secondary, adjunctive role
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ApoE2 astrocytes released more ApoE than ApoE4 astrocytes, though cellular ApoE levels were consistent across genotypes
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