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First, the conversion of methylmalonyl-coenzyme A to succinylcholine coenzyme A, by methylmalonyl-CoA mutase, with adenosyl B12 as a co-factor
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In a 2017 literature review, 39% of pseudo-TMA cases from vitamin B 12 deficiency were treated as TTP with plasma infusion or plasma exchange.9 A correct diagnosis was reached after a median of 2 weeks.9 Koshy and colleagues6 compared clinical features of patients with TTP and those with pseudo-TMA secondary to vitamin B 12 deficiency between 1997–2019
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